Interestingly, the study by Chen et al., reported a negative correlation of MYC activity and HNRNPH1 expression and a positive correlation with HNRNPF in prostate cancer, among others, while they observed the converse correlation in acute myeloid leukemia (AML), that is a positive correlation of MYC activity and HNRNPH1 expression (19). The gene discussed is HNRNPF; the disease is acute myeloid leukemia.