Additionally, we found a body weight ≤ 26 kg, CLS after HSCT, SLC29A1 (-162 + 228A>C) AC/CC genotype were independent factors for both disease-free survival (HR = 0.38, P = 0.022; HR = 2.64, P = 0.023; HR = 0.29, P = 0.016, respectively) and overall survival (HR = 0.27, P = 0.007; HR = 3.83, P = 0.003; HR = 0.22, P = 0.005, respectively). Here, SLC29A1 is linked to capillary leak syndrome.