A total of 210 SCIG infusions were performed in eight patients with immune/other thrombocytopenia and the following IEI: Wiskott–Aldrich syndrome, 4; STAT1 gain-of-function defect, 2; LRBA defect, 1; and combined immunodeficiency without genetic verification, 1. The gene discussed is STAT1; the disease is immune system disorder.