PTHLH and osteoporosis: Although spontaneous BMD recovery after weaning is well documented (10-70%) (1, 8), the efficacy of osteoporosis medications is still debated in PLAO (26, 28, 29) and the use of antiresorptive drugs, could potentially blunt post-weaning recovery in a period during which the bone loss process—driven by PTH-related protein (PTHrP) produced by the lactating mammary gland—naturally comes to an end (26, 28).