We identified 4 individuals (1.1%) with P/LP variants in BRCA2, which has previously been associated with an increased prevalence in adult myeloid malignancy, where the odds ratio for loss-of-function germline variants was 4.65 (95% CI: (2.29,9.43), P<0.0001)53. The gene discussed is BRCA2; the disease is myeloid neoplasm.