UBE2E3 and acute kidney injury: Overexpression of circRNA itchy E3 ubiquitin protein ligase (circ-ITCH) can improve renal function in SA-AKI mice and regulate oxidative stress and mitochondrial dysfunction in sepsis-induced AKI through the miR-214-3p/ABCA1 pathway, further enriching the pathophysiology of SA-AKI (61).