Ahr-Jdp2 DKO mice are embryonic lethal (unpublished data); however, knockdown of Jdp2 in Ahr KO mice has been used to demonstrate enhanced tumorigenesis of LSL-kRASG12Dp53lox/lox pancreatic adenocarcinoma 21. Here, JDP2 is linked to pancreatic adenocarcinoma.