Clinical analysis revealed a significant positive correlation between the expression levels of IGF2BP3 and OLFML1, OLFML1 and CD133, IGF2BP3 and CD133 as well as OLFML1 and GLI1, IGF2BP3 and GLI1 in serial sections from the same CRC patients (Fig. 9A-B and S6A-D). This evidence concerns the gene OLFML1 and colorectal carcinoma.