The study identifies the CXCL8‐ACKR1, CXCL2‐ACKR1 and CXCL3‐ACKR1 ligand‐receptor pairs as critical contributors to macrophage‐to‐endothelial cell signalling in IC/BPS patients.43 Here, ACKR1 is linked to Bartsocas-Papas syndrome 1.