Autoimmune and systemic vasculitis screenings were negative, including anti-nuclear antibody (ANA), anti-neutrophil cytoplasmic antibody (ANCA) [myeloperoxidase (MPO), proteinase 3 (PR3)], complement levels, cryoglobulins, and antiphospholipid antibodies. Here, PRTN3 is linked to necrotizing vasculitis.