AKT1 and small cell lung carcinoma: Propofol also suppressed small cell lung cancer growth and promoted apoptosis through the microRNA-21/phosphatase and tensin homolog/protein kinase B (miR-21/PTEN/AKT) signaling pathway in A549 non-small cell lung cancer (NSCLC) cells, both in vitro and in vivo in nude mice [12].