FKBP5 and psychosocial stress measurement: By investigating the expression and function of FKBP51 in the adrenal cortex utilizing C57Bl/6n mice and an adrenal cortex‐specific KO of Fkbp5, this study aims to shed light on the potential contribution of adrenal FKBP51 in the response to acute and chronic stress to HPA axis function and stress‐related disorders.