Recent lncRNA studies have revealed key regulators of CC progression, such as upregulation of LncRNA PCGEM1 expression in CC cells, which promotes CC progression through the miR-642a-5p/KIF5B axis [26]; LncRNA LINC00649 expression is increased in CC tissues, and LINC00649 expression serves as a prognostic predictor and exacerbates cervical cancer progression by targeting miR-216a-3p [27]; FOXD2-AS1 enhances the growth, invasion, and migration of oral squamous cell carcinomas by modulating the miR-185-5p/PLOD1/Akt/mTOR signaling pathway [28]. This evidence concerns the gene PCGEM1 and oral cavity squamous cell carcinoma.