TNFSF14 and Miyoshi myopathy: Myeloma-defining events, often termed CRAB (hypercalcemia, renal dysfunction, anemia, bone lesions) criteria and/or biomarkers of malignancy (SLM, ≥ sixty% bone marrow plasma cells, involved uninvolved serum-free light chain ratio > 100, one or more lesion detected on MRI) [1], differentiate smoldering (no-MM-defining features) from overt/symptomatic MM.