The rs61816761 variant in the FLG gene (c.1501C>T; p.Arg501Ter) (OMIM*135940; ICD‐11 EB00.2) is a stop‐gain mutation that leads to premature termination of the filaggrin protein, commonly associated with atopic dermatitis and ichthyosis vulgaris. This evidence concerns the gene FLG and atopic eczema.