These findings are consistent with earlier studies showing that transplantable tumors fail to grow in B6-deficient mice38,39 and with reports that cancer cells are “addicted” to vitamin B6 due to a dependency on the PLP-dependent enzymes ornithine decarboxylase (ODC1) and glutamic-oxaloacetic transaminase 2 (GOT2).40 Here, ODC1 is linked to cancer.