These findings align with previous observations that CBFβ-SMMHC modulates the function of GATA2 for leukemogenesis (40), Gata2 deficiency delays leukemogenesis by Cbfb-MYH11 (41), and Myc is required for the survival of inv(16) leukemia-initiating cells (42). Here, MYH11 is linked to leukemia.