MX1 and leukemia: These results suggested that the full-length CBFβ-SMMHC and CBFβ-SMMHC-ΔHABD block normal hematopoiesis and upregulate inflammatory responses, which may contribute to leukemia development in Mx1-CreCbfb+/56M and Mx1-CreCbfb+/56M-ΔHABD mice.