HP and Aphasia: In this work we used the MR paradigm to investigate the association of genetically predicted CSF haptoglobin levels with the risk of catastrophic aSAH, defined as aSAH with fatality or non-fatal aSAH with any of the following neurological complications within 7 days: hemiparesis, aphasia, apraxia, or visual field defects, but also explore associations with other related health outcomes.