Each macrophage is associated with a subcellular variable or phenotype\documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$p \in [0,1]$$\end{document} which governs its behavior: anti-tumour macrophages, also called M1, have low p values, extravasate from blood vessels, migrate toward tumour cells (up spatial gradients of the diffusible species CSF-1), and attempt to kill them on contact. Here, CSF1 is linked to neoplasm.