As with IGF2BP2 and PLAU, CEP55 has been identified as a marker for HNSCC as well.37 CMYA5, namely cardiomyopathy-associated 5, is a gene associated with cardiomyopathies.21 CMYA5 has been detected as a DEG between lymph node-positive and negative OSCC patients.23 The role CMYA5 plays in OSCC requires further research. Here, PLAU is linked to head and neck squamous cell carcinoma.