However, while an inverse correlation with viral loads and the magnitude of HLA-A and HLA-B-restricted Gag-specific epitope responses in progressive infection has been reported (59, 66, –, 68), effective control of viremia is more significantly correlated with HLA-B-restricted Gag responses than HLA-A-restricted Gag-specific responses (68, 69). This evidence concerns the gene HLA-B and infection.