DICER1 and type 2 diabetes mellitus: Based on these premises, we aimed to assess whether neosynthesis of Dicer1 occurs in platelets upon activation, whether this is regulated by mTOR and Mnk1, and if this has an impact on platelet microRNA and mRNA levels, thus regulating the expression of specific target proteins, and to evaluate whether these mechanisms are deranged in platelets from patients with T2DM.