Both HVEM and lymphotoxin β receptor (LTβr) [TNF receptor superfamily member 3 (TNFRSF3)] have been detected in RA-FLS and LIGHT induces expression of monocyte chemoattractant (33, 35) molecule-1 (MCP-1), interleukin-8, macrophage inflammatory protein-1α, and intercellular adhesion molecule-1 (ICAM-1) via the LTβr (36). The gene discussed is CCL2; the disease is rheumatoid arthritis.