A similar trend was also observed in the HepG2 tumor-bearing model: The tumor volume in the PBS group was 941.46 mm3, that in the Jurkat cell group was 765.83 mm3, and that in the LAG3-apt + Jurkat group and the HER2-apt + Jurkat group decreased to 433.16 mm3 and 400.60 mm3, respectively. The gene discussed is LAG3; the disease is neoplasm.