In the A549 tumor-bearing mouse model, the tumor volumes of different treatment groups show significant differences: The average volume of the PBS control group was 1450.08 mm3, that of the Jurkat cell group was 839.23 mm3, that of the LAG3-apt + Jurkat group was 752.50 mm3, and that of the HER2-apt + Jurkat group was 605.47 mm3. This evidence concerns the gene LAG3 and neoplasm.