Among these, five GIKs, including BLK (B lymphoid tyrosine kinase), ADCK1 (AarF domain-containing kinase 1), KCNJ15 (potassium inwardly-rectifying channel subfamily J member 15), MAP3K1 (mitogen-activated protein kinase kinase kinase 1), and IGF1R (insulin-like growth factor 1 receptor), were consistently validated across at least two sepsis outcomes (FDRIVW < 0.05; Figure 2). The gene discussed is MAP2K1; the disease is Sepsis.