Tumors with a high GPR score were significantly enriched for ribosome, and those with a low GPR score were enriched for allograft rejection, antigen processing and presentation, asthma, autoimmune thyroid disease, cell adhesion molecules, chemokine signaling pathway, graft-versus-host disease, hematopoietic cell lineage, and type I diabetes mellitus (Figure 7F). The gene discussed is ALDH18A1; the disease is autoimmune thyroid disease.