IGHE and non-small cell lung carcinoma: The median serum total IgE level in NSCLC patients significantly decreased from the baseline value of 479.0 IU/ml (IQR: 267.0–754.3) to 239.7 IU/ml (IQR: 157.2–592.0) post-treatment, with a median reduction of 239.3 IU/ml (IQR: 479.0–239.7; Z = -5.133, p < 0.001).