Chemokines such as C-C motif chemokine ligand 5 (CCL5), C-C motif chemokine ligand 11 (CCL11), C-X-C motif chemokine ligand 9 (CXCL9), and C-X-C motif chemokine ligand 10 (CXCL10) are believed to be primary mediators of eosinophil-driven tumor necrosis. Here, CCL5 is linked to neoplasm.