Our results indicate that the ABCB1 gene could influence the risk of chronic rejection (GA variant in donor's rs2235013 SNP; OR: 0.13) and severe infections, either reducing it (CC variant in recipient's ABCB1 rs1045642; OR: 0.087) or increasing it (AA variant in donor's ABCB1 rs9282564; OR: 23.8). This evidence concerns the gene ABCB1 and infection.