Finally, western blotting was employed to detect the expression of apoptosis‐related protein caspase‐3, cleaved‐caspase‐3, Bcl‐2, Bak, DRP1, and FIS1 to explore the effect of FLT on apoptosis in human breast cancer cells MCF‐7 and MBA‐MB‐231 along with the mechanism. The gene discussed is BAK1; the disease is breast carcinoma.