Meanwhile, the measurements of metabolite concentration and enzyme activity showed that intracellular peroxides, including lipid hydroperoxide (LPO) and malondialdehyde (MDA), increased, and the activities of antioxidant enzymes, such as superoxide dismutase (SOD) and catalase (CAT), declined in PLB‐treated HCC cells (Figure 3C–F). The gene discussed is CAT; the disease is hepatocellular carcinoma.