The reduced DNMT1 protein levels, increased unmethylated promoter amounts, increased miR‐302a‐3p levels, and reduced ATP7B mRNA levels in PLB‐treated tumor samples further support that the DNMT1/miR‐302a‐3p/ATP7B axis mediated cuproptosis triggered by PLB in vivo (Figure 7D,G and Figure S8I,J). The gene discussed is DNMT1; the disease is neoplasm.