CXCL5 and neurodegenerative disease: 2023). CXCL5 serves as a biomarker of prognosis in neurodegenerative diseases, neuropathic pain, peripheral nerve injury diseases, and tumors (W. Zhang, Wang et al. 2020), whereas it is rarely mentioned in BP. The mechanism of BP is widely recognized to involve damage to the facial nerve due to the inflammatory response triggered by HSV infection (Morgan et al. 1995; McCormick 1972; Zimmermann et al. 2019). HSV infection contributes to the massive expression of CXCL5 through Toll‐like receptor 2 signaling (Aravalli et al. 2005).