In the tumor immune microenvironment (TIME), CXCL10 plays a central role in the recruitment of key immune effector cells, including CD8+ cytotoxic T lymphocytes (CTLs), CD4+ Th1 cells, natural killer (NK) cells, macrophages and dendritic cells, primarily through its interaction with the CXCR3 receptor. Here, CD8A is linked to neoplasm.