By increasing CXCL10 levels, these strategies aim to improve the recruitment and activation of cytotoxic immune cells, thereby enhancing the overall immune response against the tumor.76,77 In melanoma patients, increased intra tumoral CXCL10 mRNA levels prior to treatment were found to be associated with favorable outcomes following PD‐1 blockade. Here, CXCL10 is linked to melanoma.