CXCL10 and neoplasm: In addition, CXCL10 exhibits angiostatic properties and helps limit tumor progression by suppressing the formation of new blood vessels, thereby reducing the supply of oxygen and nutrients to the tumor.54 Despite these protective effects, chronic inflammation induced by persistent expression of CXCL10 can lead to immune evasion, recruitment of suppressive immune cells and creation of a tumor-permissive microenvironment.