CDK6 and breast cancer: In addition to the PCa-related targets identified in this study, it regulates cancer stem cell phenotypes by targeting CDK6 and CDC25A in glioblastoma[26] and inhibits the EMT process by targeting MUC1 in breast cancer.[27] This pleiotropic nature may explain why the GO enrichment analysis in this study shows that miR-125a-5p-related genes are involved in multiple biological processes, including cell adhesion, oxidative stress, and RNA quality control.