CD8A and Airway obstruction: Furthermore, the mechanism of asthma is related to several cell types and cytokines, including neutrophils, type 1 T helper cells (Th1), innate lymphoid type 2 cells (ILC2s), Th7 cells, and IL-6 and IL-17, as these inflammatory cells and cytokines infiltrate, leading to airway obstruction and spasms.[14,17,48] In our study, we found a significant relationship between these biomarkers and inflammatory cells, including activated B cells, activated CD8 T cells, MDSC, regulatory T cells, and Th1 cells, which showed significant differences (P < .05).