As increased IL2RB was associated with increased survival in an independent study of canine DLBCL patients undergoing chemo-immunotherapy, we investigated the translational relevance of this gene in human patients and found increased IL2RB was also associated with prolonged overall survival in a combination of 4 human DLBCL studies (Fig. 4)25. Here, IL2RB is linked to diffuse large B-cell lymphoma.