Multiple ECM nodes were positively co-enriched in all HF conditions, but more proteins were observed to be FDR upregulated in ICM-DM from the differential analysis, such as in elastic fibre assembly and collagen fibril organisation, strongly influenced by collagens (COLs), with unique upregulation in ICM-DM in proteins such as FKBP prolyl isomerase 10 (FKBP10) and elastin microfibril interfacer 1 (EMILIN1). This evidence concerns the gene FKBP10 and hydrops fetalis.