However, there was an upregulation of albumin (ALB) and transmembrane medium-chain fatty acid transport (LRP1) in addition to a downregulation of lipid droplet-surrounding perilipin (PLIN4) in ICM-DM, which may suggest an increased bioavailability of free fatty acids (FFAs) in the myocardium. The gene discussed is LRP1; the disease is diabetes mellitus.