The RNA expression of the kinase-encoding genes MAPK1 and IRAK1, the phosphorylation-dependent, peptidyl-prolyl cis/trans isomerase PIN1, the 20S immunoproteasome subunit PSMB8, and the class I MHC genes HLA-A, HLA-C, and HLA-G were upregulated in both DM and irMyositis compared to NDC. This evidence concerns the gene IRAK1 and dermatomyositis.