SLFN5 and COVID-19: In line with this, our colocalization analysis suggests a potential shared genetic basis between SLFN5 expression and COVID-19 severities43 (Fig. 5b, PP4 = 0.398), where the rs11080327-A allele is associated with increased SLFN5 expression but decreased risk of COVID-19 severity (p-value = 9.83e-4).