Similarly, in LNCaP xenograft tumours (Fig. 2m; Supplementary Fig. S9b), compared with those in normal tumours, the protein and mRNA levels of AR decreased in tumours that recurred after castration treatment (Supplementary Fig. S18c, d), whereas the protein and mRNA levels of GR increased (Supplementary Fig. S18c, d). The gene discussed is AR; the disease is neoplasm.