CD24 and familial pancreatic carcinoma: In pancreatic cancer, CD24 is coexpressed with CD44 and EpCAM in CSC populations, yet it is also expressed in more differentiated tumor cells, complicating its use as a specific CSC marker.34,145 These observations suggest that while CD24 contributes to CSC-associated signaling, its expression should be interpreted with caution and in a tumor type-specific manner.