LEFTY2 and kidney disorder: Additionally, three of the hypermethylated SCT-associated CpGs in the current study were previously reported to be associated with kidney disease, including cg18385689 (intragenic, nearest gene LEFTY2), cg19206131 (intragenic between RAB10 and KIF3C), and cg03701853 on chromosome 11 within the PRKCDBP/CAVIN3 promoter.