CYP4B1 and infection: The most common genes in the top 10 most significant differentially expressed for the response contrasts, which represent comparisons between the populations based on the change in expression over time and therefore detect differences in gene expression between the populations in response to infection [34], included CYP4B1 and RAB31, which were in the top 10 most significant genes for four of the 15 response contrasts, followed by OLFM4, TMEM45B, and TTLL1, which were in the top 10 most significant genes for three of the 15 response contrasts (Table 2).