The next generation sequencing of our original tumor sample (liver metastasis) revealed several pathological mutations (Table 3, full list of the mutations is indicated in Supplementary Fig. 6), from them, three mutations (APC, TP53 and FGFR4) were also found to be conserved in Coala cancer cell line (Table 2 and Supplementary Table 1). The gene discussed is FGFR4; the disease is neoplasm.