While few studies have investigated the impacts of antibiotics on MRSA-toxin production during IAV-MRSA infection, one study found that infection of a Δhla MRSA mutant reduced production of IL-6 and acute lung damage in IAV-MRSA co-infected animals and that linezolid was more effective than vancomycin in preventing these Hla-like pathological changes (12). This evidence concerns the gene IL6 and infection.