PRKAG2 (7q36.1) pathogenic variants have been previously linked to PRKAG2 cardiac syndrome or “AMPK disease”, including Wolff–Parkinson–White syndrome (WPWS), lethal congenital glycogen storage disease of the heart, and hypertrophic cardiomyopathy type 6 [4,5,6,7]. This evidence concerns the gene PRKAG2 and hypertrophic cardiomyopathy 6.