Moreover, overexpression of HSPB3 in human myoblasts grown under cycling conditions enhanced the expression of genes required for extracellular matrix remodeling, which supports myoblasts’ differentiation [40] as well as satellite cell activation and muscle regeneration [41,42], and is sufficient to induce the differentiation of rhabdomyosarcoma cells [18]. Here, HSPB3 is linked to rhabdomyosarcoma.