For example, mutations in the genes coding for DNAJB4 are associated with adult-onset myofibrillar myopathy with early respiratory failure [25], while mutations in the gene coding for DNAJB6 have been associated with limb-girdle muscular dystrophy (LGMD) [31,59], myofibrillar myopathy [60] and juvenile-onset proximal-distal myopathy [61]. This evidence concerns the gene DNAJB4 and limb-girdle muscular dystrophy.