HSPA1A and muscular disease: For example, overexpression of HSP72 in dystrophic mice improved body strength and muscular endurance, similar to pharmacological upregulation of HSP72 with BGP-15; these data support the notion that HSP72 induction may exert protective functions and slow-down muscle wasting and atrophy in Duchenne muscular dystrophy (DMD) and other related muscle disorders [70].