DMD and neuromuscular disease caused by qualitative or quantitative defects of dystrophin: After dystrophin [17], a large, mutated, subsarcolemmal, glycosylated protein, deficient in dystrophinopathies, alpha sarcoglycan, 50 DAG protein, first named Adhalin from the Arabic word adhala (muscle), and then the other sarcoglycans were discovered [18].