Interestingly, a study by Curiel-Cervantes et al. showed that the MSTN SNP rs1805086 was linked to higher levels of body mass index (BMI) and waist/height ratio (WHtR) in heterozygous subjects, who showed a greater total and central obesity compared to the homozygous subjects for ancestral allele AA (OR BMI > 30 kg/m). This evidence concerns the gene MSTN and Abdominal obesity.