(1→3)-β-D-glucan level: 49.1 pg/mL (94.4% reduction from peak of 880 pg/mL). Serum IL-6: 5.7 pg/mL (within normal limits; reference range <7.0 pg/mL). Concomitant resolution of fever and C-reactive protein normalization support presumptive clinical cure of invasive fungal infection. Systemic inflammatory response has significantly resolved, transitioning to the tissue remodeling phase of infection-related damage, cerebrospinal fluid culture was negative, the skin had healed, and consciousness recovered. The patient was transferred to the neurosurgery department for surgical treatment. This evidence concerns the gene CRP and fungal infectious disease.